The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
if a woman has a uterus she must be receiving progestin along with the estrogen so that's the E plus P trial that we'll talk about right if a woman has had a hysterectomy then estrogen alone is sufficient there's no risk of endometrial hyperplasia because there is no endometrium and there's an e alone trial
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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about 25 of the women in the estrogen plus progestin trial had prior use of hormone therapy and close to 50 percent of the women with hysterectomy and in the estrogen alone trial had some prior use of estrogen therapy