Standard lab tests for estrogen typically only measure estradiol, neglecting other forms and potentially missing biologically active pseudo-estrogens.

“remember when you do a lab test and you're measuring estrogen I mean first of all you're usually just messing measuring estradiol we rarely measure Estero nor estriol and men and then who how do we even know there could be a whole bunch of pseudo estrogens that are floating around that are exerting other biologic of X that are estrogen izing but you can't measure them in the serum”