Prolonged exogenous testosterone use can lead to permanent loss of natural testosterone production capacity. — Whalespan
Prolonged exogenous testosterone use can lead to permanent loss of natural testosterone production capacity.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“this has long-term consequences for males in short it just it affects the testicles negatively it will impair the testicles ability to make testosterone long-term and many men find that once they go on higher doses of testosterone replacement therapy long term they cannot get off because the testicles have essentially gone into a prolonged hibernation”
“if you are given enough exogenous testosterone you will shut down the capacity to make testosterone in very short order and within a year two years you will permanently lose that ability”