Women who continue long-term hormone therapy in observational studies are a select group who tolerate it without adverse events.

“keep in mind this is a very select group of women who are choosing to stay on hormone therapy long term because they're doing extremely well with it and they've tolerated it well and they haven't developed any of these interim events such as a heart attack a stroke a blood clot in the legs or lungs or breast cancer other estrogen sensitive cancers”