The 'timing hypothesis' or 'window idea' in menopause medicine, suggesting hormone therapy is only safe within a specific timeframe post-menopause, is being questioned.

“So, we have this idea in menopause medicine called the timing hypothesis or the window idea, right? So, the question of the timing hypothesis is what are you afraid of? What are we worried about? We're worried about blood clots. We don't want to hurt people. We're worried about cancer. We're worried about blood clots. We're worried about heart disease. But the question is is does the hormone therapy that we use apply to the data that we have? and I would argue it doesn't. And so there is a level of we don't know what we don't know. Um, but even the timing hypothesis using Premro which was the medicine used in the WHI is under question. So Susan Susan Davis from Australia just wrote a big paper questioning the timing hypothesis and say actually when you look at the data really closely even it doesn't really hold muster. We shouldn't really be forcing people to like say you cannot start hormone therapy after 60.”