Insulin is not inherently a 'bad guy' and the claim that rising blood glucose leads to endothelial dysfunction is questionable, especially given that fruit juices have been shown to improve endothelial function.

“Dr lustig says insulin is the bad guy and and I didn't really understand this but we can listen to what he says — he then goes on to say insulin is egregious and I can prove it and talks about something called a paduro mouse but — he he claims that — that that insulin is a bad guy and that blood glucose rising blood glucose leads to endothelial dysfunction — we kind of foreshadowed this earlier I thought it was interesting then in response that I could just mention that well I don't understand how fruit juice can improve endothelial function at the same time because there's lots of studies perhaps 10 to 15 that we could just rattle off right now showing that orange juice watermelon juice cherry juice many many fruit juices are shown to improve endothelial function”