Paul Saladino· MD
Now the thyroid gland is an interesting gland it makes uh and makes this predominantly t4 which is then converted to t3 in the peripheral circulation or that t4 can be converted to reverse t3
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Now the thyroid gland is an interesting gland it makes uh and makes this predominantly t4 which is then converted to t3 in the peripheral circulation or that t4 can be converted to reverse t3
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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the TSH is really only telling you about what the pituitary and is seeing in terms of t3 t4 to t4 t4 to t3 conversion so that's telling you about the di Odin ace in the brain that's making that distinction the free t3 is telling you how much peripheral t4 is being converted to t3 and then the perversity 3 is telling you how much peripheral t4 is being converted to reverse t3 which opposes t3 and so the reverse t3 opposes t3 and each of those has a completely different sort of cause
the TSH is really only telling you about what the pituitary gland is seeing in terms of t3 t4 to t4 t4 to t3 conversion so that's telling you about the di Odin ace in the brain that's making that distinction
the free t3 is telling you how much peripheral t4 is being converted to t3 and then in reverse t3 is telling you how much per if t4 is being converted to reverse t3 which opposes t3