The combination of drospirenone and 17 beta-estradiol may cause more breakthrough bleeding because 17 beta-estradiol does not stabilize the endometrium as effectively as other options. — Whalespan
The combination of drospirenone and 17 beta-estradiol may cause more breakthrough bleeding because 17 beta-estradiol does not stabilize the endometrium as effectively as other options.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“but the downsides to it as the although these sort of work very well throughout the body they at the level of the endometrium or the lining inside the uterus is um you have a little bit more breakthrough bleeding because the 17 beta estradiol does not stabilize the endometrium as much.”
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