Certain supplements can impact standard hormone assay readings, and LC-MS testing can correct inaccuracies.

“we've seen how Believe It or Not supplements that you're taking can dramatically impact the readings and we noticed this actually first in men we were getting men who would get estrogen levels back that were you know normally a male estrogen level might be 25 to 40 we'd see guys with like 200 be like that's impossible right first of all he has no symptoms of having an estrogen of 200 come to realize he's on some supplement for you know I don't know what and that's impacting with the assay you send them to get an lcms and it comes back normal”