Paul Saladino· MD
if you are sleep deprived your LH and FSH will go down your pituitary will not signal to your testicles to make testosterone that is correctable you get better sleep and your body will make testosterone
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
if you are sleep deprived your LH and FSH will go down your pituitary will not signal to your testicles to make testosterone that is correctable you get better sleep and your body will make testosterone
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if your lh and fsh are high and your testosterone is low then your testicles are not responding properly but if your lh and fsh are low then your brain is not telling your testicles to produce testosterone and that is related to stress and sleep
low testosterone is often related to lack of sleep something that i didn't really go into a whole lot in this podcast but if you are not getting enough sleep your lh and fsh will go down that is how you know if it is a pituitary cause or a gonadal cause
and not sleeping affects your testosterone because you get signals from your brain the pituitary gland send signals to your testicle to make testosterone this is FSH this is FH FSH and LH right
so what does this mean in English this means this guy's brain isn't making the signal to tell his body to make more testosterone despite the fact that his testosterone is low so that tells you where the problem is the problem is in the brain and the number-one diagnosis for that is sleep deprivation
it was probably in the low 200s throughout all of residency and not because of training just because of sleep deprivation and a whole bunch of other factors
typically when we see that pattern, the second pattern you've described, which is low testosterone, but in the setting of low LH and FSH, the most obvious things that usually show up there are poor sleep, uh, and you know, basically high gluccocorticoids, um, which can also suppress the pituitary.