Long-term combination hormone replacement therapy increases breast cancer risk, and bone loss accelerates after stopping HRT. — Whalespan
Long-term combination hormone replacement therapy increases breast cancer risk, and bone loss accelerates after stopping HRT.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“if we were to treat women from early menopause into their 70s 80s that would be very long duration of hormone therapy use which would lead especially combination hormone therapy would lead to an increased risk of breast cancer and once women go off of hormone therapy bone loss is very rapid”