Hypertension is not the sole or primary cause of small vessel disease, as many patients with small vessel disease do not have hypertension.

“if we come back earlier uh we off we we are saw that one of the cause or maybe the major cause of small disorder disease was hypertension but nowadays we know that's not the case because to give you an example here um if maybe a third even more of the cult of this is patients that we follow they don't have any hypertension first of all so it tells you that there's a big chunk of people that can move to small vessel disease so meaning adding white matter diseases that were thought to be due to hypertension and hardly damage vessels but it's not the case”