Hypertension can trigger blood-brain barrier leakage and pericyte loss, contributing to small vessel disease.

“I think that just the final point is I think it's very important the duration is the crowd The Chronic part of hypertension is very critical if you have that for many years same thing for inflammation as you age you have a chronic slow low grade information that will disrupt your vessels very slowly probably the same thing with hypertension if you have too much hypertension your table stiffness will be uh you know Disturbed and damage over time and this will degrade your preparing barrier value much faster than the normal tenses person”