Paul Saladino· MD
in individuals who were carriers or had a copy or two individuals who were carriers or ap4 there was less incidence of inflammation in response to infectious load
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
in individuals who were carriers or had a copy or two individuals who were carriers or ap4 there was less incidence of inflammation in response to infectious load
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in the setting of The the Bolivian semen a in in particular the the one study where they looked at Apple E4 genotype and cognitive function it seemed to be apple u4 seemed to be protective in the setting of a high parasitic infection burden which is common in those societies and that's probably because of improved uh immune function able to sort of you know better respond and mitigate um some of the issues that you might get from a systemic parasitic infection