Paul Saladino· MD
there are cytokines produced by inflammation and immune activation and other parts of the body to cross the blood-brain barrier and say hey there's something going on out here you guys need to be inflamed too
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
there are cytokines produced by inflammation and immune activation and other parts of the body to cross the blood-brain barrier and say hey there's something going on out here you guys need to be inflamed too
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Well, there's now going to lots of evidence showing that you know, a lot of cytokines in the periphery can cross the blood-brain barrier with a variety of mechanisms, including this newly discovered lymphatic system that's connected to the brain, the meninges or something.