Inflammation, a downstream effect of cellular glycolysis, can damage DNA and inactivate tumor suppressor genes, increasing cancer risk.

“so, downstream of a cell that's glycolytic, that's only using glucose to make ATP through this glycolysis pathway is inflammation again. I come back to it because it's just downstream of everything. And inflammation damages DNA and eventually you get it in the right gene that's saying, "Oh, this gene usually protects," whenever there's any damage, it kills a cell. It's called a tumor suppressor gene. You get it in that tumor suppressor gene, you're screwed.”