Endotoxin (lipopolysaccharide) binds to TLR4, triggering the release of inflammatory cytokines like TNF alpha and IL-6.

“Endotoxin is a word. It's a it's a synonym for lipopolyaccharide. Lipopolyaccharide is a component of a bacterial cell wall, a gram negative bacterial cell wall. So when you feed a human pure sugar, the wrong type of bacteria overgrowth. This is dispiosis. You mess up the gut flora. And that signaling of endotoxin, it binds to TLR4, which is tolike receptor 4, and you get cytoines, TNF alpha, IL6, and others, which signal inflammation in the human body, and your body says, "Whoa, I've got an infection."”