Administering a low dose of insulin (1-2 IU) to a fasted patient can facilitate glucose uptake in skeletal muscle, potentially creating severe hypoglycemia.

“you could potentially put someone on an IV right and pulse a low dose of insulin to make them hypoglycemic even one or two millimolar and then deliver some of these agents where you've really restricted the fermentable fuels so I was you know I'm a reviewer on different manuscripts that are coming in and some of these academic and and clinical oncologists are actually suggesting this and léo medical hypothesis papers now and that's kind of counterintuitive because you'd think well we don't the last thing you want to do for a tumor is give it insulin because this is so because they say also tile and it's acute and the amount of insulin it's not like 20 IU's it's something like 1 or 2 IU's so patient comes in fasted and you give them just a little bit and that's facilitating mostly facilitating glucose uptake in the skeletal muscle so making it less available for the tumor right and that creates a scenario where you produce severe what would typically be fatal hypoglycemia and you could deliver ketones you know as an insurance”