Taking significantly less insulin to achieve normal glycemia represents a substantial improvement in health outcomes.

“which is that insulin while an amazing and important hormone is not benign and there's a big difference between taking a hundred units of insulin a day to achieve normal glycemia and taking 20 units of insulin a day to achieve normal glycemia and you'll take the latter over the former all day every day non-negotiable and some patients will say well gosh i'm still on insulin this hasn't worked and not realizing no you've had a five-fold reduction in your insulin requirement that's an enormous improvement in your health outcome”