Insulin binding to its receptor initiates a signaling cascade that leads to the translocation of GLUT4 transporters to the cell surface, facilitating glucose uptake.

“So putting that in English for folks, insulin hits this transmembrane tyrosine kinase. And when the molecule of insulin hits it inside the cell, this kinase pathway kicks up, it moves the GLUT4 transporter. Well, there's another step in there, but oversimplifying a little bit, that chemical reaction is necessary to translocate this transporter across the cell to bring glucose in.”