Insulin resistance is a vague and nonspecific term due to the many actions of insulin in the liver, muscles, and in response to glucose, amino acids, and fat.

“the actions of insulin are so many yes it has an action in the liver it has an action in the muscles it has an action with response to glucose it has an action with response to amino acids and it has an action with response to Fat both in the liberation of fat uh lipolysis and presumably in response to oxidation”

“one of the challenges with the term insulin resistance is as you said it's a vague term and it's nonspecific because the actions of insulin are so many it has an action in the liver it has an action in the muscles it has an action with response to glucose it has an action with response to amino acids and it has an action with response to Fat both in the liberation of fat uh lipolysis and presumably in response to oxidation”