Phlorizin inhibits SGLT2 and SGLT1 transporters, blocking glucose and phosphate transport in the kidney.

“I knew that there was a molecule called Florin that blocked glucose transport uh in the kidney and so I took this molecule called Florin and it blocks the uh glucose Transporters there are two Transporters in the kidney sglt2 and sglt1 sglt2 takes back 90% of the glucose if it does its job sglt1 takes back the other 10% and then in your I even even though we filter 180 gram of glucose per day no glucose appears in the urine but what I showed is that Florin it blocked both sglt2 and sglt1 it blocked glucose transport uh and it also blocked phosphate transport”