Lowering uric acid with allopurinol may be beneficial for insulin resistance, kidney disease, and blood pressure control.

“now although in animals allopurinol is totally protective or protects a lot against sugar-induced metabolic syndrome the data in humans is suggestive so there's been for example four pilot studies showing an improvement in insulin resistance with lowering uric acid in humans all four are positive there's a lot of trials in kidney disease showing that lowering uric acid may benefit kidney disease there's data on blood pressure we had a paper in the jama showing that oil and uric acid could improve blood pressure control in adolescence with hyperuricemia so there's a lot of supporting data”