Individuals with insulin resistance maintain normal glycemia because their pancreatic beta cells compensate by producing two to three times the normal amount of insulin.

“and both of these things go hand in hand because of course as is obvious I guess to people now when those glucose levels are chronically elevated the body wants to fix it they it wants to crank up more insulin as the solution to the resistance so the resistance is at the cell where the insulin signal isn't being heard so the pancreas just yells louder and it makes more and more insulin”