The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
one of the physiologic processes that happens in a ketogenic diet is called beta oxidation that's how we break down fatty acid molecules and part of how ketones are made well as it turns out beta oxidation is also the pathway by which hne is broken down and in studies and animal models which probably have the same physiology as humans putting animals into a ketogenic state increased beta oxidation and led to higher levels of hne breakdown
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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I guess there probably really is a reasonable hypothesis here that if you have diabetes and insulin resistance some term of ketogenesis maybe maybe cyclic ketogenesis maybe six months to a year may improve your body's disposal of these aldehyde breakdown products as that linoleic acid is broken down or oxidized in your human body maybe people with diabetes really should be on a ketogenic diet to upregulate beta oxidation to quote unquote detoxify hne it's a compelling hypothesis that I think needs to be tested
doing a low carbohydrate diet doing a very low carbohydrate diet may be beneficial by up regulating beta oxidation my colleagues in the ketogenic world would be very excited that I'm saying this because I've not been super excited about ketogenic diets for many of you in the past and upregulation of beta oxidation may help us get rid of hne faster May improve this process so I think that's a reasonable thing to do for many of you who are in this position