Leptin resistance can compromise immune system function, potentially leading to a cytokine storm.

“Ron talked a lot about elect and resistance and it goes hand in hand with insulin but he just described that leptin itself partakes in many parts of the immune system it is a cytokine in itself when you become leptin resistant which all insulin resistant people will be your leptin is elevated and he described how your immune system in in both ways warned the parents of your immune system that should be quite aggressive are not so much so and the part that overflows the cytokine storm that actually kills people and that's also completely compromised by diabetes leptin resistance”