Paul Saladino· MD
activation of pro-inflammatory pathways and and oxidative stress contributes to hyperinsulinemia and insulin resistance
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
activation of pro-inflammatory pathways and and oxidative stress contributes to hyperinsulinemia and insulin resistance
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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experimentally if you produce a state where there's oxidative stress and you produce a pro-inflammatory state you get insulin resistance and pretty profound