The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So they did not gain weight. They did not become insulin resistant. We didn't see elevation in C-peptide, clenicosyloid hemoglobin. So by all characteristics, those mice were normal. They were not insulin resistant. they still had increased polyps by two to three fold size.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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And as a side issue, along the lines you're saying, we actually found in the case where we had the water fed rather than a fixed amount, the 12-ounce soda equivalent, that the subset of mice that had the APC mutation actually were protected from insulin resistance. There was polyps reading so much of the sugar that it was protecting the mouse from becoming insulin resistant.
And we also tried feeding them only glucose, the same number of calories of glucose or the same number of calories of fructose versus the mixture of glucose plus fructose. And they had to have both sugars, fructose and glucose, before the polyps would grow faster.