Rhonda Patrick· PhD
Can one bad night’s sleep trigger insulin resistance?
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Can one bad night’s sleep trigger insulin resistance?
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Even a single night of sleep restriction can cause acute insulin resistance
One bad night of sleep will result in a much higher and disrupted rhythm of cortisol. And and so cortisol is will cause insulin resistance in every biological model very quickly.