Paul Saladino· MD
If you consume fat and carbohydrates in excess you will eventually reach your personal fat threshold and become insulin resistant.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
If you consume fat and carbohydrates in excess you will eventually reach your personal fat threshold and become insulin resistant.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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there's what we take in our diet and it does look like to me you can make you can eat yourself into insulin resistance I think we're pretty clear that you can eat yourself an insulin resistance and to me it looks like based on the Randle cycle their biochemistry which we don't have to go into here if we consume fat and carbohydrates in excess which is basically extra doughnuts yeah right the easiest way to consume fat and carbohydrates and access to sweet processed food which is often fat and sugar in excess we will eventually get to our personal fat threshold at which the adipocyte says whoa No Mas and we become insulin resistance starting from the adipose tissue