Gastric bypass surgery can rapidly normalize insulin sensitivity by delivering food lower down in the gut, balancing GIP, GLP, and PYY.

“the fastest ways to reverse insulin resistance is to get a gastric bypass because you're then delivering that food much lower down into the gut and then you'll start you almost immediately normalize some of that increase in physiology so so eat without surgery yet people without losing any weight they all of a sudden become much more insulin sensitive because because you're now delivering foods to the part of the gut that is expecting it at the right time and then this is kind of the balance between GIP GL p and p YY and probably other inc returns”