The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so what I like about Jason's model is it gets rid of the discordance between how can you have an insulin resistant muscle and an insulin sensitive fat cell mechanistically to which I've never had a compelling response
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
he has a very interesting model of insulin resistance which is that it's not actually resistance it's just basically the storage tank is full so the elevated level of glucose is because the glycogen stores are basically tapped out and the elevated level of insulin is not because the insulin receptors and/or the intracellular mechanistic transducers are themselves quote-unquote resistant it's just trying to push harder and harder to get the glucose in