Pancreatic beta cells sense blood sugar spikes to release insulin, which signals body cells to absorb glucose.

“the way that you regulate your glucose the way that you sort of have glucose homeostasis is that there are at least two major parts of this equation the first is that cells in your pancreas called beta cells need to sense the spike in blood sugar and then they need to release insulin and then when that insulin is released it actually tells the cells of the body to reach out and absorb the blood glucose the blood sugar and that prevents you from an otherwise dangerous spike in blood sugar”