Dietary changes can induce insulin resistance by decreasing inflammation and creating caloric deficits or stopping adipocyte overfeeding.

“and so and like you said and people with inflammatory disorders they get insulin resistance sooner you know I think this is one of the fascinating things of dietary change inducing insulin resistance is it it's probably a combination of can we affect decreasing levels of inflammation by removing inflammatory foods processed food or in my opinion perhaps some plant foods which are triggering information in the guy who knows and can we create temporary caloric deficit or stop over feeding people or stop the sort of physiology that leads to this a tipo site over feeding as we're stuffing extra calories into people”