The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Gerald Shulman has done a lot of work on the mechanism by which insulin affects glucose transport in muscle I don't want to speak for him I mean in terms of what he thinks about this but he certainly is one of the people who I think has advanced the field in terms of understanding why for example ambient fatty acids seems to suppress glucose uptake in muscle
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
um so I think what Gerald Shulman has done is to advance our understanding of a very I think compelling mechanism by which high levels of ambient fatty acid themselves might suppress insulin signaling some of that fatty acid could in fact come from lipid that's stored in the muscle as opposed to lipid or fatty acids that are in the circulation