Hyperinsulinemia and other subtle markers of insulin resistance are more informative for type 2 diabetes than genetic predisposition.

“does it help me to know that someone has a genetic predisposition to type 2 diabetes not nearly as much as it helps me to know while they are still non-diabetic that they have hyperinsulinemia and even if they don't have while fasting to know that they have postprandial hyperinsulinemia it's very important to look at other subtle markers of insulin resistance the elevation of fertin some of the other things that we see other patterns of glucose disposal these things matter a lot more”