Age-related insulin resistance leads to elevated glucose levels, impaired glucose transport into nervous tissue, increased insulin release, and subsequent desensitization of insulin receptors, contributing to metabolic syndrome.

“because as you pointed out the insulin resistance because our glucose levels are going up because we cannot transport it into the tissue especially nervous tissue which was a primary consumer has effectively and then we have these high levels of glucose for longer times so there's more insulin there is being released and then these desensitizes their receptors so there is a natural developing of metabolic syndrome as we grow all because of this phenomenon”