Peter Attia· MD
I maintain the state of ketosis throughout that whole mission and and did lots of lots of measurements myself down there and I saw really when I one time I got out after maybe it was a six-hour a VA so essentially you're hyperbaric habitat on the bottom of the ocean and then you go out into the water and then you come back inside the hyperbaric habitat but when you're out in the water even though you're down in the keys the water water pulls heat from you like 200 times faster than air so even though it's like you know upper 80s I come out of that hypothermic and dehydrated my blood glucose always was in like the 30s sometimes in the 40s when I was on Nikita I was testing some of the ketone supplements Wow what were the other people experiencing under those circumstances well we'll find out with this my wife actually is a was selected as a crew member for NASA and you know 23 I was on 22 and I did not get the IRB protocol approved to do all the metabolic studies that I wanted to do but I became an n of one on that and I collected a lot of data on myself so with this new mission we have the Nemo NASA Nemo 23 we'll be able to make some pretty comprehensive metabolic measurements including things like hemoglobin h 1c we're going to measure inflammation H s CRP glucose ketones all these things on all the crewmembers interestingly this year it's a it's an all-female crew so you have like Samantha Christopher Eddie the famous European Tracy Caldwell Dyson who I've known at NASA and my wife and it's all female so we'll have love some female data to go along with this what surprised you the most in your end of one what did you see that you'd least expected I saw why predicted that the habitat would really trigger inflammation that was probably from the elevated co2 levels and the elevated oxidative stress I chose to stay in a state of ketosis with the idea that that was my baseline state we're doing Studies on sleep we're using the oral ring you're probably familiar with that on sleep and and also the polar V 800 to collect heart rate variability data gut microbiome we're doing body composition measurements we're doing stress so we use the NIH toolbox and to look at cognitive psych parameters so that data has not been shared to me so I don't know my wife collected some of that data and that's being analyzed you know later on for publication but from a metabolic perspective from a hormone perspective some of the things living in that environment for 10 days decrease my testosterone unless I had a 25% decrease in testosterone from the time and so we're fairly may be fairly sleep-deprived I average about 6 hours of sleep per night but I was getting like 2 and a half hours of deep sleep which is more deep sleep very typically yeah I was like I don't know if it's a it's simply an artifact of how the sleep is being estimated in other ways you know if you think you're assuming you're giving that off the aura ring right yeah that was also the aura ring is measuring but I usually get about 90 minutes sometimes like last year last night I got one hour and 53 minutes of deep sleep but I usually get about one out one and a half hours of deep sleep but I got over two hours every night and instead of seven hours sleep at night I was getting consistently just you know five to six hours sleep at night so where are you gonna be shortchanged on REM yeah but my REM was even not that bad I was getting about an hour you know an hour around which is not as much yeah usually two is optimal for me I think so yeah we measured sleep the things that really stood out were being in the water really pushes my body into and being hypothermic really turns me into a fat-burning machine my ketones go off the chart and my glucose goes way down and almost looks like a six-hour evie a when I came back into the habitat look like I fasted for a week so I have all that data for that two that I need to compile and now should we be looking at that we meaning people as a potential way to replicate fast under a more stressful state looking at what just underwater he do you think it was a combination of temperature and pressure primarily that was driving that effect so over the holidays we went to Thailand and we did I did a lot of nitrox dives something like thirty nitrox dives and I made these measurements too and I did see trends decrease glucose and nitrox dyes were doing like an hour maybe hour hour-and-a-half diets at the most and I saw trans but nothing like the trends I saw in the saturation environment when we did these long EPA's so do you think that the temperature was that pretty sure the temperature really has to have