Ketosis is not a physiologically stressful situation for the human body within one to three weeks.

“I think from Chris's perspective gluconeogenesis is somehow stressful I do not find evidence for this at all if you look at what happens and many of the studies looking at gluconeogenesis will suggest that in the acute phase ketosis increases stress hormones cortisol maybe you even see a bump in terms of pH you might even see a slight decline in the blood pH in the acute phase of the transition to ketosis but what it's very seldom talked about is that within seven to the days to three weeks all of these changes normalize and blood pH normalizes bicarbonate levels normalize levels of cortisol in the body normalize and so when people say ketosis is stressful gluconeogenesis is stressful it's it's not clear to me that that is the case”