Patients treated with ketogenic or very low carbohydrate diets for years may be able to reintroduce some carbohydrates without negative consequences, suggesting a potential reset of metabolic function.

“have you treated patients for long enough on ketogenic or very low carbohydrate diets who showed up in a state of metabolic disarray ran through a lengthy period of this so you know maybe spent years on a carbohydrate restricted protocol and everything gets better so they you know the weight goes along for the ride but obviously and more importantly their metabolic markers improve and they gradually reintroduce some amount of carbohydrate back in the diet and all of a sudden they're fine almost as though you reset them during a long enough period”