Paul Saladino· MD
the sirtuin genes these genes all get turned on with beta hydroxy butyrate
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
the sirtuin genes these genes all get turned on with beta hydroxy butyrate
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all the effects that we are claiming are beneficial from polyphenols we can achieve in other ways whether it's turning on longevity genes like sirtuin ones we know we can do that with ketosis
the process of ketosis does all of the same things so when you are in ketosis and you have beta hydroxy butyrate in your body because you are not doing glycolysis your nad levels are high you are getting nad from ketosis it's the ratio right the ratio of nad at NAD+ yeah nad to NADH and so the state of ketosis with beta-hydroxybutyrate mimics sirtuin gene activation through exogenous resveratrol
when you are in ketosis you can activate many of the same genetic mechanisms that resveratrol will activate specifically sir two and one