Paul Saladino· MD
if you give a macrophage a native LDL molecule... the macrophage will not take that LDL up that LDL must be oxidized to be taken up by the macrophage
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
if you give a macrophage a native LDL molecule... the macrophage will not take that LDL up that LDL must be oxidized to be taken up by the macrophage
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there's really no evidence that native LDL damages the endothelium there's potentially evidence that oxidized LDL within the intimal space can damage the endothelium once the ldl's been oxidized by a macrophage
there's really no evidence that native LDL damages the endothelium there's potentially evidence that oxidized LDL within the intimal space can damage the endothelium once the ldl's been oxidized by a macrophage