While some experts consider LDL particle number the best predictor of cardiovascular risk, Paul Saladino believes this may be an evolutionary fallacy.

“those guys would say hey LDL particle number is the best predictor we have to tell people that LDL particle number is is dangerous and so they would caution people in these states my thinking about that is this and this is where it gets into some really interesting evolutionary sort of anthropology talk is how could something that is evolutionarily consistently bad for us and that maybe is my own fantasy and maybe that's a logical a logical fallacy or thought it's a hard one to argue on that position”