Consuming a diet higher in leucine stimulates the mTOR pathway, which can increase fatty acid accumulation in muscle and liver, chronic liver glucose production, increased insulin secretion, increased beta cell reproduction, and increased risk for beta cell suicide.

“so I'm not an expert by any stretch the imagination but the reading that I've done has actually showed that when you consume a diet that's higher and loosing that it stimulates the mTOR pathway which then increases fatty acid accumulation inside of muscle and liver chronic liver glucose production increased insulin secretion increased beta cell reproduction and increased risk for beta cell suicide”