The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
And when there's lots of these three branched-chain amino acids, particularly leucine, it will be activated. And this mTOR, the role is to say, wow, I got lots of amino acids, let's build muscle, let's repair cells, let's do all good stuff, which is why you you feel good if you eat red meat and your microbiome can handle it.
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So, now you've got these amino acids circling in your body, circulating, and there are three ones that are particularly important to know about, it's leucine, ISO leucine and valine also known as the branched-chain amino acids. And these are used by the body to sense protein intake. And the sensor is this protein complex we talked about called mTOR.
and we're back to that teleological argument why did muscle learn to sense that because that basically shows up in the blood in direct proportion to the meal and the muscle learned to sense that as a meal quality it says oh wow this meal has adequate quality for me to to trigger this very expensive process of protein synthesis protein turnover and until it sees that signal it won't do it