Peter Attia· MD
when most of the PSA that you have in your blood is um bound very limited amounts of free PSA that's a strong marker that there's something going on I.E that cancer cells are leaking the PSA into the bloodstream
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
when most of the PSA that you have in your blood is um bound very limited amounts of free PSA that's a strong marker that there's something going on I.E that cancer cells are leaking the PSA into the bloodstream
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as PSA is evolving in the normal kind of development of its exocrine function it gets snipped into smaller and smaller States fully fully processed PSA can float around in the bloodstream freely that's free PSA
it is not designed and it should not exist in the blood but a certain percentage of PSA made in prostatic epithelial cells leaks into the bloodstream and when we do a PSA blood test we're measuring the PSA that has leaked into the bloodstream from a prostatic epithelial cell