Peter Attia· MD
in a drug trial what you'll do is you'll take individuals and you'll randomize them either to a drug arm or a placebo arm and then you'll look for an outcome there's an intervention which is the assignment of the drug or the placebo and then you can actually check to see whether the outcome is correlated to that particular intervention and if you see an effect Now that effect is attributable to that intervention because the decision to give the intervention versus the placebo was done randomly if you didn't do it randomly you can't make that assertion Now in a Mendelian randomization experiment the idea is that there's a randomization that took place at birth