Germ-free mouse models infused with a human microbiome are used to study the human microbiome's impact on host health.

“so they literally make I call them like the Bubble Boy of Of Mice so they try to entirely deplete these mice of microbiomes so they're taking a mouse that has no microbiome and then they're infusing them with a human microbiome and they're saying okay what happens now to the mouse um and so these are germ-free Mouse models that are really commonly used to understand the impact of a human microbiome on the health of the animal this is completely not what would ever happen in real life”