Targeted therapies like Gleevec work by synthesizing a chemical to jam cancer-specific engines without affecting normal cells.

“so this was identified that the exact the gene product was I didn't find a protein product of the gene was identified and then through an elaborate series of experiments in circumstances chemists found a way to actually Jam the engine one molecule human beings may we stitch this molecule together it's a remarkable achievement and once the engine is jammed which suddenly turns out that the disease goes into remission this was one of the first examples there others of so-called targeted therapy where you take you synthesize a chemical to Jam cancers engines in a cancer specific way it doesn't affect normal cells”