Strong mechanical stimuli like tugging or inflation of viscera can elicit physiological responses such as increased blood pressure and heart rate.

“The viscra don't typically respond to the same type of stimuli that uh no susceptive pain does. You'll remember when you were taking a boi um to the bowel, the small intestine, patients wouldn't normally move because the noiceptors don't respond to that. But if you tug on it, if you pull that or inflate it or inflate it, boy oh boy, blood pressure goes up, heart rate goes up.”